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In chronic HBV infection, numerous studies have confirmed the heterogenous pattern of infected hepatocytes in chronic HBV infection (Figure 1) where infection is spread intermittently throughout the liver in patches comprised entirely of infected cells [21,23,24,25,26,27,28] or in sparsely infected regions [21,24,25,27,29,30]

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Amount of Capsules:5 Capsules (sample)

Bax, a pro-apoptotic protein, is upregulated and undergoes a conformational change upon DNA damage or oxidative stress, triggering apoptotic signaling (62)