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Treatment with divalent metal cations like copper and iron augment oligomerization of α-synuclein during challenge with DOPAL, a neurotoxic byproduct of dopamine metabolism [81], and treatment with vitamin C prevents α-synuclein oligomerization by inhibiting the oxidation of DOPAL [81] or interaction with copper [82]

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doi: 10.1016/j.ijporl.2015.06.008 [DOI] [PubMed] [Google Scholar] 43.Beukes EW, Manchaiah V, Allen PM, Andersson G, Baguley DM